Older info, some may still be useful I'm busy trying to get old 8mm film to scan properly using this scanner. (Send me your feedback using the form at the bottom of the page)

iscan works, both standalone and as a gimp plugin (File→Create→Scanning).

xsane now works, but it sounds like the scanner is moving its head in the wrong direction when initializing (?!).

in /etc/sane.d/nf, change the line usb to:.

in /etc/sane.d/dll.conf, make sure the line with epson is uncommented (you can leave epkowa and epson2 commented out).

install in this order: iscan-data, iscan, iscan-plugin-gt-x750.

download the core & data packages, and the iscan plugin package for Linux (for CentOS 6.4 I needed the ltdl7 version of the first RPM): iscan-2.29.2-1.usb0.1.ltdl7.x86_64.rpm iscan-data-1.24. iscan-plugin-gt-x750-2.1.2-1.x86_64.rpm.

from the Epson download center page, search for '4490'.

The steps I took are listed below (maybe not all are required, but at least the scanner works now :-) ) Update: getting the scanner to work under CentOS 6.4 x86_64 Recently I got the scanner to work again under CentOS 6.4. A clear advantage of this scanner was the high quality high res scanning capability, a clear drawback the poor build quality. Sane-find-scanner still reports it, but any other software says there's no scanner attached. Update: after about 8 years of service, my 4490 did one more scan of some 8mm film, and then decided to call it quits :-( (related tip: fixing the Epson 4490 ratchet noise)

Epson scanner 4490 driver download